We have numerous molecular biological techniques, transgenic mice (CRISPR knockouts, Cre-lox tissue-specific knockout, optogenetic and GCamp3 lines), neuroanatomical tract tracing, electrophysiology (current and voltage clamp), telemetry, immunocytochemistry, stimulus dependent and independent measures of rodent behavior and access to both clinical databases and specimens. The body of this work includes the role of neurotrophins during neurodevelopment/apoptosis(NGF/TrkA & NT3/TrkC), axon guidance molecules during development (semaphorins), the role of chemokines/receptors in adult rodent injury models (CCL2/CCR2 and CXCL12/CXCR4), the influence of toll-like receptor-4 (TLR4) in the peripheral nervous system, study of drug-induced changes in voltage-gated sodium channels such as NaV1.7, and the influence of damage-associated molecular patterns (DAMPs) and their cognate receptors in both neuropathic pain syndromes and following traumatic brain injury.Īs PI or co-investigator on several university-, state-, NIH- and DOD-funded grants, I have established productive intramural and extramural research collaborations allowing me to utilize a variety of injury models including a newly developed closed head injury in mice. His hobbies include hiking, travel, reading, ACDs and social issues.Ī large proportion of my research has been directed at the influence of tissue-derived factors on the nervous system during development and following disease/trauma. Many of these events may be critical for the discovery of new mechanisms and targets for chronic pain treatment. His research group studies the sequence and nature of the neuroinflammatory events that govern neuron and non-neuronal communication in the nervous system following injury in both pre-clinical models and clinical subjects. White is an expert in the field of chronic pain mechanisms. White joined Indiana University School of Medicine in October 2009 and became the Vergil K. He joined the faculty of Loyola University Stritch School of Medicine as an assistant professor (Cell Biology, Neurobiology and Anatomy, 2002-2009) where he rose to associate professor and director of research for the Department of Anesthesiology. He was appointed as an associate research scientist at Yale University School of Medicine in both the Departments of Neurology and Anesthesiology (1999-2002).
William Snider and Massachusetts General Hospital/Harvard Medical School (Anesthesia and Critical Care, 1998-1999) with Dr. His graduate work was followed by postdoctoral training at Washington University in St. White received a Bachelor of Art (Psychology, 1985) from Baldwin-Wallace College a Master of Science (Pathology, 1990) and a doctorate (Anatomy and Neurobiology, 1994) from the Medical College of Ohio. White with a multitude of resources for conducting basic and translational research.ĭr. His experience in medical/graduate education and university leadership positions at two nationally recognized medical schools-Loyola University, Chicago, and Indiana University School of Medicine-provides Dr. White, PhD, is a medically-trained neuroscientist involved in both pre-clinical and clinical research studies for nearly 30 years.
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